Bone Marrow Transplant Center of the First Affiliated Hospital, Zhejiang University School of Medicine has a long history and excellent academic tradition, integrating comprehensive development in medical care, education, and research. The Cellular Therapy and BMT Workshop Program is designed to provide comprehensive education and training on the latest developments and techniques in cellular therapies and hematopoietic cell transplantation.

During your training, your responsibilities increase with your experience, capability, and performance. You will become highly skilled in the multi-disciplinary management of hematological diseases especially with innovative cellular therapies (e.g. CAR-T cells) and hematopoietic cell transplantation, and gain extensive experience with the clinical and research tools needed for a successful academic career in this field.

The target group mainly includes medical practitioners, clinical researchers, residents, and fellows specializing in hematology, oncology, and related disciplines who are interested in expanding their expertise in cellular therapy and hematopoietic cell transplantation techniques. The workshop involves lectures, hands-on training sessions, and interactive discussions led by experts in the field.

• Engaging in both standard patient care and advanced cellular therapy and stem cell transplantation for patients through personalized mentorship with experienced physicians.

• Gaining direct access to our esteemed faculty who are highly reputable experts both domestically and internationally. The expert team led by Prof. He Huang not only excels in patient care but is also dedicated to advancing medical frontiers.

• Comprehensive didactic training program including weekly grand rounds led by Prof. He Huang, bi-weekly journal club, in-person and online fellows' education series.

• Joining intimate morning rounds within a medical group led by a top expert in cellular therapy or hematopoietic cell transplantation, where newly admitted patients are discussed, inpatient management strategies are assessed, and bedside educational sessions.

• Exceptional research opportunities for those interested in pursuing groundbreaking basic research and translational work in cellular therapy and transplantation.

• Opportunities to undertake clinical research projects.

• Lectures given and clinical rounds led by internationally leading experts such as Prof. Mohty, Prof. Didier Blaise, Prof. Thierry Facon, Prof. Edmund Waller etc.

• Focusing on cutting-edge medical technologies in the fields of cellular immunotherapy and hematopoietic stem cell transplantation and, the program invites medical talents from around the world for exchange and training, enhancing their cross-cultural communication skills and cultivating top medical talents with an international perspective, thereby promoting innovative development in the field of hematology.

• Participants will systematically learn advanced clinical technologies for the diagnosis and treatment of malignant hematological diseases through various methods such as lectures by experts, discussions on difficult cases, clinical teaching, research projects, and on-site visits.

• In addition to clinical medical skills, the curriculum covers cutting-edge technologies and methods in the basic research of hematology, including molecular biology, omics, and big data analysis, allowing participants to understand the latest research techniques and findings in the field, thereby enhancing their research capabilities and literacy.

The program provides a full-time, 2-week to 6-month training experience. In special circumstances, arrangements can be made for other lengths of training depending on your needs and interests.

• Fellows: Qualified applicants for the Hematology Fellowship must have completed a general internal medicine residency program at an accredited institution.

• Residents: To be eligible for the Hematology/internal medicine residency, you must have successfully completed a board-approved program in internal medicine. Your internal medicine program may be completed either through Zhejiang University School of Medicine or another accredited program.

• Students:

1. Must be a final-year medical student when you are scheduled to participate in the rotation. This means all your core / required clerkship rotations are complete at the time of the clinical elective.

2. Medical School Approval - Letter of good standing from the dean’s office of your medical school indicating you are in the final year with your expected graduation date, in good academic standing and meet all requirements to complete an elective for academic credit.

Focus Areas & Subspecialties:

1. Acute leukemia

2. Multiple myeloma

3. Lymphoma

4. Anemia (e.g. aplastic anemia)

5. CAR-T immunotherapy

6. Hematopoietic cell transplantation (autologous OR allogeneic)

7. Multidisciplinary team management

Skills:

1. Basic skills: bone marrow aspiration, lumber puncture, etc.

2. Laboratory skills: bone marrow morphology, flow cytometry report interpretation, NGS report interpretation, Clinical study design and data analysis

Monday

1st day of week: introduction & welcome, program overview and objectives

Campus visit of Yuhang campus, Bone Marrow Transplantation Center and Liangzhu Laboratory

Weekly: Clinical rounds and academic lectures

Tuesday

Weekly: journal club, clinical rounds, outpatient observation, academic lecture

Focus: hematopoietic cell transplantation patient rounds and bedside teaching; instruction and Q&A on theoretical knowledge related to hematopoietic cell transplantation; cutting-edge technologies and research progress in hematopoietic cell transplantation.

Biweekly: mentor one-on-one training

Wednesday

Weekly: discussion of difficult cases led by Prof. Huang, and multidisciplinary team (MDT) meetings.

Weekly: clinical rounds, outpatient observation, academic lecture

Focus: bedside teaching for patients receiving CAR-T cell immunotherapy; research progress in CAR-T cell immunotherapy; instruction and Q&A on theoretical knowledge related to CAR-T cell immunotherapy.

Biweekly: mentor one-on-one training

Thursday

Weekly: journal club, clinical rounds, outpatient observation, academic lecture

Focus: patient rounds and bedside teaching on other hematological diseases including multiple myeloma, leukemia, etc.; instruction and Q&A on theoretical knowledge clinical trial design, international collaboration, clinical data analysis, etc.

Biweekly: Mentor one-on-one training

Friday

Weekly: Journal club, Clinical rounds, outpatient observation, Academic lecture

Weekly: Academic lectures on frontier basic research in hematological diseases. Free discussion with leading experts on basic research.

Last Week: Wrap-Up & Reflection, Participant presentations or discussion of key takeaways, Feedback session (e.g. online survey or live Q&A)

After each rotation, each faculty member evaluates each fellow according to core competencies of patient care, medical knowledge, practice-based learning and improvement, interpersonal and communication skills, professionalism, and system-based practice. Faculty members meet with fellows individually for verbal feedback and evaluation. Monthly, an aggregate evaluation of a fellow's clinical progress is conducted through a clinical competency faculty committee.

The program is free of charge.