This program is tailored to train early-career researchers and students in Sjogren Syndrome immunotherapy research. It aims to equip participants with both theoretical knowledge and hands-on skills, preparing them for advanced academic or industry careers in biomedical science. The target group includes graduate students, research fellows, and postdoctoral researchers passionate about Sjogren Syndrome.

· Weekly mentorship meetings with Prof. Wu and a multidisciplinary research team.

· Access to advanced laboratory facilities, including flow cytometry and so on.

· Real-time involvement in clinical trials and translational research projects.

· Opportunities to publish articles or abstracts in peer-reviewed journals and present research posters or papers at conferences.

· Critical thinking, analytical, and practical inquiry skills utilizing the latest approaches in healthcare and medical research.

· Skills in critical appraisal, research design, and understanding of the entire medical research process.

· Understand the principles and applications of Sjogren Syndrome immunotherapy

· Develop proficiency in cutting-edge laboratory techniques, such as single-cell sequencing

· Gain experience in clinical trial design and analysis

· Cultivate skills in scientific writing and grant preparation

3 weeks

Rsearch focus:

1. Clinical trial of Yangyin Yiqihuoxue prescription in treating Sjögren's syndrome.

2. The gut microbiota microenvironment of Sjogren's syndrome.

3. Pathogenic mechanisms of Sjögren's syndrome including inflammation and immunity

Projects:

1. Clinical efficacy of Yangyin Yiqi Huoxue prescription combined with hydroxychloroquine in the treatment of Sjogren's syndrome

2. Gut-Oral/Axonal Mechanism of Action in Sjögren's Syndrome

3. Exploring the Mechanism of Treating Sjogren's Syndrome with Nourishing Yin, Tonifying Qi, and Promoting Blood Circulation Formula Using Multi omics

Undergraduate students:

Candidates should be enrolled in a bachelor's degree program in biology, biochemistry, or a related field. Prior coursework in molecular biology or immunology is preferred. Basic proficiency in English is required.

Graduate students:

Candidates must be enrolled in a Master’s, M.D. or Ph.D. program in biomedicine, immunology, or a related field. Familiarity with research methodologies and laboratory techniques is required. Fluency in English is mandatory.

Researcher fellows:

Applicants should have an advanced degree (M.Sc. M.D. Ph.D. or equivalent) in a biomedical discipline with some prior research experience. Candidates must demonstrate an ability to work independently and contribute to team projects. Proficiency in English is essential.

Doctors:

Candidates must hold an M.D. degree with clinical experience, preferably in internal medicine. Research experience is not mandatory but is a strong advantage. Applicants must be fluent in English.

Postdocs:

Postdoctoral fellows should have a Ph.D. in biomedicine, immunology, or an M.D. with clinical training in medicine, or the equivalent of education, training and experience. Candidates should be fluent in English.

Daily Training Schedule:

Daily Training Schedule:

Monday:

9:00 AM – 12:00 PM: Lecture on Basics of Immunology

1:00 PM – 3:00 PM: Wet lab training: cell culture

Tuesday:

10:00 AM – 12:00 PM: Workshop on bioinformatics tools

2:00 PM – 4:00 PM: Journal club: Discussing recent papers in immunotherapy

Wednesday-Friday:

9:00 AM – 11:00 AM: Data analysis for clinical trial results

11:30 AM – 12:30 PM: One-on-one mentorship meetings

Program Training Schedule:

1. Introduction & Welcome

Time Duration: (1 day)

Activities:

Workshop overview and objectives

Introduction of facilitators/tutors

2. Foundational Session

Time Duration: ( 1 week)

Topics:

Key concepts and theories related to the research focus

Literature review or background studies

Format: Lecture, interactive Q&A, or multimedia presentations

3. Practical/Hands-On Session

Time Duration: (3 weeks)

Activities:

Demonstrations of research tools or methods (e.g. lab equipment, software)

Practice exercises where participants replicate a research technique

Guided small-group activities for solving a case or analyzing data

4. Focused Research Topics

Time Duration: (3 weeks)

Topics:

Specialized areas of the research focus (e.g. recent trends, challenges, or advanced techniques)

Format: Interactive lectures, panel discussions, or guest speakers

5. Collaborative Session

Time Duration: (1 week)

Activities:

Group projects or brainstorming sessions

Problem-solving exercises or simulations

6. Wrap-Up & Reflection

Time Duration: (2 days)

Activities:

Participant presentations or discussion of key takeaways

Feedback session (e.g. online survey or live Q&A)

Assessment Methods:

Submission of a final research report summarizing lab work and findings

Practical assessments during wet lab sessions

Certificates provided upon successful completion of the program

Feedback for Participants:

Participants can submit anonymous feedback via an online form at the end of the program. One-on-one feedback sessions will also be scheduled midway through the program.

The program is free of charge.