Background:

Biomimetic mineralization creates materials with superior properties and biocompatibility by mimicking natural processes. Type I collagen, widely used in biomedical materials, benefits from enhanced properties when incorporating specific elements. Despite its suitability for guided bone regeneration membranes, collagen membranes face limitations like barrier duration and osteogenic induction. Strontium, a vital trace element, promotes bone formation and angiogenesis, inhibiting bone resorption. Thus, research on strontium-doped biomimetic mineralized collagen membranes is crucial.

Purpose:

To advance biomedical materials by researching strontium-doped biomimetic collagen membranes' preparation, optimization, and applications.

To enhance medical students' knowledge and research skills.

Target Group:

Students majoring in stomatology 

Centered on clinical needs, this project incorporates strontium into collagen membranes, enhancing their properties and offering clinical value. It covers multiple disciplines, educating students on biomedical advancements and boosting their professionalism through hands-on experience. 

Prospected Outcome：

Develop a novel biomedical material integrating biomimetics, mineralization, and strontium's biological effects for efficient bone repair. This project aims to advance biomedical materials and offer superior solutions for clinical bone defect repair.

Goal：

Theoretical knowledge acquisition

Experimental skills enhancement

Innovative capacity cultivation

Team collaboration and communication skills

Research areas:

1. Digital Implant Dentistry

2. Biomimetic Mineralization

3. Guided Bone Regeneration

Projects:

1. Fabrication of biomimetic strontium-doped mineralized collagen membrane for bone regeneration.

2. Clinical Study on Immediate Functional Rehabilitation of Full-Arch Implant-Supported Prosthesis in Edentulous Jaws Using Digital Technology.

Undergraduate students:

You should have completed the relevant foundational coursework, and an interest in bone biomimetic materials.

Graduate students:

You should have completed the relevant foundational coursework, certain research capabilities, and an interest in bone biomimetic materials.

Duration: 12 weeks

Program Training Schedule:

1. Preparation and Characterization of Collagen Membranes

2. Biomimetic Mineralization Techniques

3. Material Evaluation

4. Summary and Presentation

Individual Mentorship: Mentors meet regularly with participants for personalized feedback and support.

Progress Reports: Participants submit periodic reports summarizing work and challenges, which mentors review and provide feedback on.

The program is free of charge.

Program Coordinator: GU Xinhua

Email: guxh@zju.edu.cn

Phone: